A new method for autozygosity mapping using single nucleotide polymorphisms (SNPs) and EXCLUDEAR
نویسندگان
چکیده
منابع مشابه
A new method for autozygosity mapping using single nucleotide polymorphisms (SNPs) and EXCLUDEAR.
T he development of a silicon chip, such as the Affymetrix 10K Xba 131, bearing sufficient oligonucleotides to analyse 10 913 single nucleotide polymorphisms (SNPs) presents a new method for seeking autosomal recessive loci. This letter describes a practical strategy to analyse the data output of such an ‘‘SNP-chip’’ for this purpose. Autozygosity mapping, first suggest by Lander and Botstein, ...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 2004
ISSN: 1468-6244
DOI: 10.1136/jmg.2003.016873